14-3-3 epsilon Polyclonal Antibody-BS90002

14-3-3 epsilon Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS90002-50, BS90002-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P62258(Human) P62259(Mouse) P62260(Rat) Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, ICC/IF, IHC, FC All Applications: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:10-1:100 Background: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell d