14-3-3 Theta Rabbit mAb - A8936

14-3-3 Theta Rabbit mAb Sizes: 20µl, 100µl Catalogue Numbers: A8936-20, A8936-100 Citations, Manuals and SDS Available upon request. Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. Synonyms: 1C5; HS1; 14-3-3; 14-3-3 Theta GeneID: 10971 Swiss-Prot: P27348 Reactivity: Human, Mouse, Rat Calculated Molecular Weight: 28kDa Observed Molecular Weight: 28kDa Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 Theta (P27348). Immunogen Species: Human Host: Rabbit Isotyp