53BP1 Polyclonal Antibody - RA21503

53BP1 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: RA21503-50, RA21503-100 Citations, Manuals and MSDS Available upon request. Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Store at: -20°C/1 year Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Alternative Names: TP53BP1; Tumor suppressor p53-binding protein 1; 53BP1; p53-binding protein 1; p53BP1 Background: function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is required for DNA binding.,PTM:Phosphorylated at basal level in the absence of DNA damage. Hyper-phosphorylated in an ATM-dependent