5HT2C Receptor Polyclonal Antibody-BS90010

5HT2C Receptor Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS90010-50, BS90010-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P28335(Human) P34968(Mouse) P08909(Rat) Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, IHC All Applications: WB:1:500-1:2,000 IHC:1:50-1:200 Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system