A1CF Polyclonal Antibody - E-AB-66005

A1CF Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-66005-60, E-AB-66005-120, E-AB-66005-200 Citations, Manuals and MSDS Available upon request. Abbreviation: A1CF Target Synonym: A1CF; ACF; ACF64; ACF65; APOBEC1CF; ASP Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: IHC Isotype: IgG Clonality: Polyclonal UNIProt ID: Q9NQ94 Background: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA proces