A2ML1 Rabbit pAb - A17831

A2ML1 Rabbit pAb Sizes: 20µl, 100µl Catalogue Numbers: A17831-20, A17831-100 Citations, Manuals and SDS Available upon request. Background: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. Synonyms: OMS; p170; CPAMD9; A2ML1 GeneID: 144568 Swiss-Prot: A8K2U0 Reactivity: Human, Rat Tested Applications: ELISA, WB Calculated Molecular Weight: 161kDa Observed Molecular Weight: 161kDa Immunogen