AADAC Polyclonal Antibody - E-AB-14453

AADAC Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-14453-60, E-AB-14453-120, E-AB-14453-200 Citations, Manuals and MSDS Available upon request. Abbreviation: AADAC Target Synonym: AAAD; Aada; Aadac; Arylacetamide deacetylase (esterase); Arylacetamide deacetylase; CES5A1; DAC Research Areas: Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: WB, IHC, ELISA Isotype: IgG Clonality: Polyclonal UNIProt ID: P22760 Background: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen d