ABL1 Polyclonal Antibody - E-AB-60067

ABL1 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-60067-60, E-AB-60067-120, E-AB-60067-200 Citations, Manuals and MSDS Available upon request. Abbreviation: ABL1 Target Synonym: ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; ABL1; c-Abl; bcr/abl Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Rat Application: WB, IHC, IF Isotype: IgG Clonality: Polyclonal UNIProt ID: P00519 Background: This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle