ABL2 Polyclonal Antibody-BS90015

ABL2 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS90015-50, BS90015-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P42684(Human) Q4JIM5(Mouse) Unigene:69847(Rat) Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, FC All Applications: WB:1:1,000-1:2,000 FC:1:50-1:100 Background: The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including chronic myelocytic leukemia (CML), in which it undergoes a (9;22) chromosomal translocation and produces the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein tyrosine kinase. The related protein tyrosine kinase Arg, also de