ACACB Rabbit Polyclonal Antibody - RA21572

ACACB Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA21572-50, RA21572-100 Citations, Manuals and MSDS Available upon request. Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Store At/In: -20°C/1 year Recommended Dilutions: WB 1：500-2000 Background: acetyl-CoA carboxylase beta (ACACB) Homo sapiens Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008], Appl