ACAT1 (K266) Polyclonal Antibody-BS3796

ACAT1 (K266) Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS3796-50, BS3796-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P24752 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, IHC All Applications: WB: 1:500~1:1000 IHC: 1:50~1:200 Background: ACAT-1 (acetyl-Coenzyme A acetyltransferase 1) is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. Rare defects in the gene encoding ACAT-1 lead to β-ketothiolase deficiency, which is characterized by ketoacidotic attacks. ACAT-2 (acetyl-Coenzyme A acetyltransferase 2) is considered a cytosolic protein and is crucial for cholesterol synthesis. Specifically, both Acetoacetyl-CoA specific thiolases, ACAT-1 and ACAT-2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction, the cleavage of acetoa