Acetyl-Histone H3-K4 Rabbit mAb - A24340

Acetyl-Histone H3-K4 Rabbit mAb Sizes: 20µl, 100µl Catalogue Numbers: A24340-20, A24340-100 Citations, Manuals and SDS Available upon request. Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. Synonyms: H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3