ACLY Polyclonal Antibody - E-AB-10986

ACLY Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-10986-60, E-AB-10986-120, E-AB-10986-200 Citations, Manuals and MSDS Available upon request. Abbreviation: ACLY Target Synonym: ACL; Acly; ACLY; ATP citrate (pro-S) lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPcitrate synthase; ATPCL; Citrate cleavage enzyme; CLATP; OTTHUMP00000164773 Research Areas: Cancer, Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: IHC, ELISA Isotype: IgG Clonality: Polyclonal UNIProt ID: P53396 Background: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP an