Recombinant PDL1-Fc fusion protein

Background Programmed Death Ligand 1 (PDL1) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. It is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. PD-L1 binds to its receptor, PD-1, found on activated T cells, B cells, and myeloid cells, to modulate activation or inhibition. Recombinant PDL1-Fc fusion protein Source: HEK 293 cell-derived.Recombinant PDL1-Fc protein is human PDL1 (amino acids 19-239) fused with mouse IgG1 Fc protein at the C-terminus.Purity: >95% by SDS-PAGE under reducing conditions.Formulation: 0.2 μM filtered solution of 50 mM Tris, 150 mM NaCl, pH 7.5.Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.Shipping: The product is shipped with ice pack. Upon receipt, sto