Tremelimumab biosimilar, human CTLA-4 monoclonal antibody

Recombinant Chimeric IgG2 Monoclonal Antibody.Isotype: Human IgG2 kappa.Source: The anti-human CTLA-4 monoclonal antibody tremelimumab biosimilar (research grade) was produced in mammalian cells.Specificity/Sensitivity: The in vivo grade tremelimumab biosimilar specifically binds to the human protein receptor CD152 / CTLA4.Applications: ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying biological pathways affected by tremelimumab.Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.Purity: >95% by SDS-PAGE under reducing conditions and HPLC.Shipping: The research grade tremelimumab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date