Recombinant Mouse ROR1 Protein

Product Overview Description Recombinant Mouse ROR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln30-Tyr406. Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC Accession Q9Z139 Target Symbol ROR1 Synonyms ROR1; NTRKR1; dJ537F10.1 Species Mouse Expression System HEK293 Tag C-His Expression Range Gln30-Tyr406 Mol. Weight The protein has a predicted MW of 43.28 kDa. Due to glycosylation, the protein migrates to 58-68 kDa based on Tris-Bis PAGE result. Form Lyophilized Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Endotoxin Less than 1EU per ug by the LAL method. Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Shipping Shipped at ambient temperature. Gene Background ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),- is a member of- the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.