Primary Human Brain Microvascular Endothelial Cells (ACBRI 376)

Primary Human Brain Microvascular Endothelial Cells (ACBRI 376) were initiated by elutriation of dispase-dissociated normal human brain cortex tissue. Primary Human Brain Microvascular Endothelial Cells can provide a useful tool for adherence, transport and permeability studies of the blood-brain-barrier (BBB).  ACBRI 376 cells demonstrate particular markers of differentiation (interdigitated cell contact, desmosomes, Z0-1 protein epitopes) similar to those observed in vivo.  The morphological and immunofluorescent markers detailed for ACBRI 376 are suggestive of a differentiated cell monolayer that can be used to study properties of the human BBB. Click For Current Applications and Assays Using Cell Systems Primary Human Brain Microvascular Endothelial Cells (ACBRI 376)     ACBRI 376 cells 3 days after plating, plated with Attachment Factor™, cultured in Cell Systems Complete Medium Kit With Serum and CultureBoost-R™ (4Z0-500-R). ACBRI 376 cells express endothelial cell mark