Human Genome-Wide CRISPRi sgRNA Library
Pooled sgRNA Library targeting all human protein-coding genes and designed to work with deactivated spCas9 (dCas9) complexed with the KRAB repressor to inactivate or down regulate gene expression. Five sgRNA to each gene target. Library includes 3,700 non-targeting sgRNA controls. Designs based on Horlbeck, et al., eLife 2016;5:e19760 DOI: 10.7554). Manual and Product Documentation Manual: CRISPR Pooled Lentiviral sgRNA Libraries Gene List: Human Genome-Wide CRISPRi sgRNA Library Gene List Flyer: CRISPRa and CRISPRi Human Genome-Wide Libraries Library Vector Information * Sequences are available in FASTA (.txt), GenBank (.gb), and SnapGene (.dna) formats. You may use the free SnapGene Viewer to open .dna files. If you would like vector files in another format, please contact us. To download .txt and .gb files, right click on the link and Save As. Search Product Certificates by Lot# or Catalog# Alignment Software Supporting Files Library Configuration File (JSON for