B6/B1 Plus Zinc - 90 Capsules

Vitamin B6 (pyridoxine) toxicity has been reported at dosages above 300 mg per day for extended periods. However, the biologically active form of vitamin B6, pyridoxal‐5‐phosphate (P5P), has no reported toxicity. Therefore, P5P is the preferred form of vitamin B6 for higher utilization. While Vitamin B1 is widely distributed in the food chain, highly refined foods are virtually absent in thiamin, thus a diet high in these foods will ultimately be low in thiamin. Functionally, thiamin is a part of the coenzyme thiamin pyrophosphate (TPP), also known as cocarboxyase, and is a required component in the metabolism of carbohydrates as a part of the coenzyme thiamine cocarboxylase. Specifically, TPP “is required for the oxidative decarboxylation of pyruvate to form acetyl‐coenzyme A, providing entry of oxidizable substrate(s) into the Krebs cycle for the generation of energy. Additionally, it is also a coenzyme for transketolase, which functions in the pentose phosphate pathway, an alte