Alexa Fluor® 488 anti-Cytokeratin 19

Cytokeratin 19, also known as keratin 19, is a type I intermediate filament protein with a molecular weight of approximately 40-44 kD. Cytokeratin 19 is a heterotetramer composed of two type I and two type II keratin subunits. Unlike other cytokeratins, cytokeratin 19 lacks a C-terminal non-helical extension. This cytokeratin is widely expressed in the periderm (transient superficial layer enveloping developing epidermis), muscle, intestine, bile duct, esophagus, stomach, and thymus. Cytokeratin 19 can be upregulated by vitamin A and is thought to play a critical role in embryogenesis. Cytokeratin 19 intereacts with the pinin protein and has been shown to be modified by phosphorylation (Ser10, Ser35).PRODUCT DETAILSClone: A53-B/A2Antibody Type: MonoclonalReactivity: HumanFormat: Alexa Fluor 488Host: MouseIsotype: IgG2a, κApplications: ICC - Quality testedRegulatory Status: RUOData Sheets: TDS | SDSNote to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an