Alexa Fluor® 488 anti-human CD161

CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.PRODUCT DETAILSClone: HP-3G10Antibody Type: MonoclonalReactivity: Human, Cynomolgus, RhesusFormat: Alexa Fluor 488Host: MouseIsotype: IgG1, κApplications: FC - Quality testedRegulatory Status: RUOData Sheets: TDS | SDSNote to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cy