CD11b Monoclonal Antibody (M1/70), Brilliant Violet™ 480, eBioscience™

PRODUCT DETAILSHost: RatIsotype: IgG2b, kappaClonality: MonoclonalClone: M1/70Format: Brilliant Violet™ 480Reactivity: MouseApplication: Flow CytometryTested Dilution: 0.25 µg/testConcentration: 0.2 mg/mLStorage: 4° C, store in dark, DO NOT FREEZE!Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2Purification: Affinity chromatographyData Sheet: TDS Specific InformationDescription: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.Applic