CD127 Monoclonal Antibody (eBioRDR5), Super Bright™ 780, eBioscience™

PRODUCT DETAILSHost: MouseIsotype: IgG1, kappaClonality: MonoclonalClone: eBioRDR5Format: Super Bright™ 780Reactivity: HumanApplication: Flow CytometryTested Dilution: 5 µL (0.5 µg)/testConcentration: 5 µL/TestStorage: 4° C, store in dark, DO NOT FREEZE!Formulation: PBS, pH 7.2, containing 0.09% sodium azidePurification: Affinity chromatographyData Sheet: TDS Specific InformationDescription: The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak