CD170 (Siglec F) Monoclonal Antibody (1RNM44N), Brilliant Violet™ 711, eBioscience™

PRODUCT DETAILSHost: RatIsotype: IgG2a, kappaClonality: MonoclonalClone: 1RNM44NFormat: Brilliant Violet™ 711Reactivity: MouseApplication: Flow CytometryTested Dilution: 1.0 µg/testConcentration: 0.2 mg/mLStorage: 4° C, store in dark, DO NOT FREEZE!Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2Purification: Affinity chromatographyData Sheet: TDS Specific InformationDescription: This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of