CD8a Monoclonal Antibody (53-6.7), Brilliant Ultra Violet™ 805, eBioscience™

PRODUCT DETAILSHost: RatIsotype: IgG2a, kappaClonality: MonoclonalClone: 53-6.7Format: Brilliant Ultra Violet™ 805Reactivity: MouseApplication: Flow CytometryTested Dilution: 0.5 µg/testConcentration: 0.2 mg/mLStorage: 4° C, store in dark, DO NOT FREEZE!Formulation: PBS, pH 7.2, containing 0.09% sodium azidePurification: Affinity chromatographyData Sheet: TDS Specific InformationDescription: The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development an