cFluor® B532 Anti-Human CD19 (HIB19)

The HIB19 monoclonal antibody binds to human CD19, a 95-kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. CD19 forms a signal transduction complex with the complement receptor 2 (CD21), a tetraspanin membrane protein, TAPA-1 (CD81), and Lue 13 to function as a dominant signaling component on the surface of B cells1,2. It is expressed in all phases of B cell development, maturation and differentiation except at the terminal stage of differentiation, lost in plasma cells3. It is also present on follicular dendritic cells and absent on T cells. The antibody was conjugated to a fluorophore and purified by affinity chromatography.   PRODUCT DETAILS Clone:                  HIB19 Reactivity:          Human, Chimpanzee, Rhesus Format:              cFluor® B532* Isotype:               Mouse IgG1, κ Tested Dilution:  5 μL / test Application:        Flow Cytometry Storage:               2-8°C and protected from Light. Do not freeze Formulation:       Phosphate-buffered soluti