cFluor^® V715 anti-Human CD3 (UCHT1)

The UCHT1 monoclonal antibody binds to the human epsilon chain of the CD3 antigen/T cell antigen receptor, a 20- to 30-kDa protein complex. This complex contains a CD3γ, a CD3δ, a CD3ζ (CD247), two CD3ε, and a T cell receptor (α/β or γ/δ) heterodimer (Dong, D., et al. 1981. Nature. 573, 546–552). CD3 is found on all mature T cells, NKT cells, and thymocytes. It plays a role in recognizing antigen, activating cytotoxic T cells and T helper cells, and signal transduction (Weiss A, et al. 1991. Semin Immunol. (5):313-24). The antibody was purified by affinity chromatography and conjugated to the fluorophore. PRODUCT DETAILSClone: UCHT1Reactivity: HumanFormat: cFluor® V715Isotype: Mouse IgG1Tested Dilution: 5 μL / testApplication: Flow CytometryStorage: 2-8°C and protected from light. Do not freeze.Formulation: Phosphate-buffered saline, pH 7.2, containing 0.1% PEG 3350, 0.1% Pluronic F-68, 0.05% Tween-20, 0.09% sodium azide and 1% BSA (BSA Country of Origin USA)Data Sheets: TDS SDSEXAMPLE