Muse^® Human CD8 T Cell Kit

The Muse® Human CD8 T Cell kit is used in laboratory research studies to determine the CD8+ T cell count, total lymphocyte count, and percent of CD8+ T cell lymphocytes in human whole blood and peripheral mononuclear cell (PBMC) samples. Identification and enumeration of cytotoxic CD8+ T cell populations are useful in understanding immune response and status, and in the research of disease mechanisms, such as autoimmune diseases and immunodeficiency. The Muse Human CD8 T Cell kit allows for the detection and identification of lymphocytes and CD8+ T lymphocytes in both whole blood and PBMCs using a simplified, no-wash assay. The CD8 antibody allows the identification of CD8, a 68 kDa transmembrane glycoprotein expressed by class I major histocompatibility complex-restricted, mature suppressor/cytotoxic T cells, which are the majority of cortical thymocytes and approximately 30 percent of medullary thymocytes. Additionally, a portion of γδ T cells and NK cells express CD8. Inclusion of