Allium sativum Lectin (ASA) - Pure

Allium sativum lectin (ASA) is isolated from garlic bulbs and purified with affinity chromatography. It is a dimer of two subunits. ASA binds to several α1-2-linked mannose residues. The lectin recognizes internal mannose and binds to the core pentasaccharide of N-linked glycans. In addition, the removal of sialic acids enhances binding activity. The binding site can withstand terminal sialic acid and galactose residues. The blood group specificity of ASA is towards rabbit erythrocytes and weak interaction with human erythrocytes. ASA has shown antiproliferative and apoptosis-inducing activity, making it a relative subject in cancer research. Applications: Cell typing, Anticancer, Glycobiology Recommended Usage: 1XPBS (pH 7.4) buffer should be used to reconstitute the Lyophilized Cake. Less than 0.5 ug /ml will agglutinate rabbit erythrocytes.