3D Printed Carcinoma of Pyriform Fossa

3D Printed Carcinoma of Pyriform Fossa Clinical HistoryA 60-year old male presents with a 6-week history of globus (i.e. the feeling of a lump in his throat) and dysphonia. On examination, he had enlarged cervical lymph nodes. Investigations discovered a laryngeal tumour. He underwent a laryngectomy and a cervical lymph node dissection. He made a full recovery. Pathology The specimen is the amputated larynx viewed from behind. It shows an irregular fungating tumour arising from the left pyriform fossa. There is distortion and oedema of the laryngeal tissues. Histologically, this was a squamous cell carcinoma. Further InformationOver 95% of laryngeal cancers are squamous cell carcinomas (SCC). The tumour usually develops on the vocal cords but may occur above or below the cords, on the epiglottis, aryepiglottic folds or in the pyriform sinuses. The cancer usually begins as carcinoma in situ, progressing to ulcerated, fungating invasive carcinoma with continue