Tildren 500mg (30 mL) for Horses

Tildren 500mg (30 mL) for Horses Tildren belongs to a class of drugs called bisphophonates.Bisphophonates prevent the loss of bone mass and are used in humans to inhibit bone resorption by blocking activity of osteoclasts, to increase bone density and to inhibit secretion of enzymes that degrade cartilage on joint surfaces. In horses, Tildren is used to treat navicular syndrome, hock disease (spavin) and kissing spine syndrome. Some veterinarians see the drug as a new avenue to manage diseases that are characterized by circumstances in which the bone breakdown process exceeds the bone rebuilding process. If bone loss can be limited during the inflammatory and degenerative processes, it is thought that a positive effect on bone structure and reduction of pain are possible. In a horse with navicular or other chronic bone conditions, such as ringbone, for example, or osteoarthritis of the hock, Tildren acts to inhibit bone deconstruction by shutting down what are known as osteoclasts. O