EGFP-fused APP (Amyloid precursor protein) HEK293T Cells

EGFP-fused APP (Amyloid precursor protein) HEK293T Cells Catalog # C20001   For in vitro use only   Description EGFP-APP is an EGFP-fused APP (Amyloid precursor protein) protein, of which gene in 293T cells EGFP gene is inserted to its N-terminal by Homologous Recombination(HR). Hence, endogenous APP expression is replaced by EGFP-APP. Background Alzheimer’s disease is the most common neurodegenerative disease in senior people. One important factor causing the disease is derived from formation of amyloid plaques in brain. Amyloid production comes from an ectopic degradation of Amyloid precursor protein (APP). The endogenous EGFP-APP fusion protein is useful for exploring the degradation, localization, transportation and function of APP in 293T cells. Host Cell  293T cells Contents  1 vial contains > 2 x 106 cells in freezing medium.  Thawing of Frozen Cells  1. Upon receipt of the frozen cells, it is recommended to thaw the cells and initiate the culture immediately in order to