Calprotectin (S100A8/A9) ELISA for Human Stool (ImmuChrom)

Description The Immuchrom Calprotectin (S100A8/A9) ELISA Kit is an immunoassay intended for the quantitative determination of calprotectin in human stool samples. For research use only. Summary Human calprotectin is a dimer which consists of the subunits S100A8 (10.835 kDa) and S100A9 (13.242 kDa). The monomers are able to bind calcium. The complex is located in the cytosol of neutrophils and is excreted to the intestine while inflammation. The concentration of fecal samples correlates with the severity of inflammatory processes in the intestine. The complex is resistant against enzymatic degradation. The measurement of fecal calprotectin represents an easy non-invasive analysis of intestinal inflammation with the possibility to differentiate between noninflammatory irritable bowel disease and intestinal inflammation accompanied with morphological alteration of the intestinal mucosa. In case of viral or bacterial infections of the gut the concentration of calprotectin in feces is incr