Macrophage Colony-Stimulating Factor 1 (M-CSF) Mouse, E. coli Recombinant Protein

Description Macrophage Colony-Stimulating Factor 1 (M-CSF) Mouse, E. coli Recombinant Protein is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 156 amino acids and has a total molecular mass of 36.4 kDa. M-CSF is purified by proprietary chromatographic techniques. Summary Macrophage colony-stimulating factor (M-CSF) is a cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membra