PAN-Biotech Mycorase 50X Solution for Mycoplasma Removal
Introduction Mycoplasma contamination of cell cultures (primary cultures as well as cell lines) continues to present a considerable and often disregarded problem for basic academic research and bio-pharmaceutical manufacturing using cultured cells as major tools. Comprehensive surveys have demonstrated the presence of different strains of mycoplasma in up to one third of cell cultures tested. Infected cells may show morphological as well as functional changes, such as decreased or shutdown proliferation or diminished production of cellular metabolites. In addition, an infection may occur unnoticed, resulting in undesired deviations of cellular function. Therefore, a frequent examination for possible contamination with mycoplasma and an effective treatment are essential for a successful work with cell cultures. Mycorase has been developed to remove a broad range of different strains of mycoplasma in most cell types. Mycorase is easy to use and does not affect eukaryotic cell proliferati