Stem Cell Factor (SCF) Human, Sf9 Recombinant Protein

Description Our bioactive Stem Cell Factor (SCF) Human, Sf9 Recombinant Protein is a single, glycosylated polypeptide chain containing 165 amino acids and has a molecular mass of 18,409 Dalton. The SCF is fused to a C-terminal His-tag (6xHis) and purified by proprietary chromatographic techniques. Summary Stem cell factor (SCF), also known as KIT ligand, binds to the receptor-type protein-tyrosine kinase KIT (CD117). This pleiotropic cytokine plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. SCF exists in both a soluble and a transmembrane isoform. SCF is commonly used in cell cultures in vitro to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells. Other Names KIT ligand, c-Kit ligand, KITLG, KL, KL-1, KITL, mast cell growth factor, MGF, Steel factor, SF Source Sf9 insect cells Formulation Sterile f