Corning BioCoat Collagen IV-coated Flasks

Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation.Applications include:Promotion of cell attachment and spreadingCell differentiation and neurite outgrowthIncreased proliferation of PC12 cellsStudies of effects of collagen IV on cell behaviorCell adhesion assaysSourceEngelbreth-Holm-Swarm (EHS) lathrytic mouse tumorQuality ControlTested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cellsTested and found negative for bacteria and fungiCollagen IV purity >90% by SDS-PAGEStorage2°C to 8°C. Do not freeze.Ordering Information - Packaging:354523 - Case/5354528 - Case/10Brochure:Click Here for Brochure