Total Estradiol (LC/MS) & Free Estradiol (Equilibrium Dialysis)

Estradiol (E2) plays a vital role in hormonal balance, metabolism, cardiovascular health, and neurological function in both men and women. While total estradiol reflects overall circulating levels, it does not indicate how much is biologically active. This test measures both total estradiol (LC/MS) and free estradiol (Equilibrium Dialysis), providing the most precise evaluation of estrogen bioavailability. Dual-measurement of Total & Free Estradiol is particularly valuable for individuals on hormone therapy, assessing testosterone-to-estrogen balance, or experiencing symptoms that do not align with total estradiol levels alone. By distinguishing between bound and active estradiol, it offers deeper insight into how estrogen is functioning in the body.