Clinical Guide to Depression and Bipolar Disorder: Findings from the Collaborative Depression Study

Author: Martin B. Keller MDPublisher: American Psychiatric PublishingPaperback:ISBN 10: 1585624330ISBN 13: 978-1585624331Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study builds on research from the vastly influential NIMH Collaborative Depression Study (CDS) to provide clinicians with information they can use to assess, diagnose, treat, and understand how their patients will likely fare over the course of their illness. Prior to the CDS, there had been no longitudinal study of this scope and clinical focus, and the data has yielded knowledge that, enriched by ongoing research, provides essential guidance to mental health practitioners for effective treatment of their patients with mood disorders. The volume s editors and contributors are experts in mood disorder research, and they have created a work of uncommon value and utility. After a succinct but thorough summary of the history and methodology of the CDS, the book highlights the significance of CDS findings on mood disorders, including major depressive disorder and bipolar disorder, with emphasis on clinical course, interventions, and outcomes. Chapters on genetic factors and comorbidities provide critical context, and chapter-ending summaries of clinical implications help to highlight the importance of the CDS findings for clinical practice. Concise, authoritative, and evidence-based, Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study will be a welcome resource for mental health clinicians. Review This work is a veritable tour-de-force, a Who's Who of scholars and scientists in mood disorders, and a treasure trove of data and practical clinical advice. I am inspired by the duration of this heroic study, its magnitude and import, and by the patients who magnanimously allowed themselves to be subjects over decades. I particularly valued the clinical pointers at the conclusion of chapters. Every psychiatrist will want this book within easy reach. --Alan J. Gelenberg, M.D., Shively/Tan Professor and Chair, Department of Psychiatry, Penn State University, Hershey, PAThe Collaborative Depression Study involved a 31-year follow-up of about 1,000 patients who had mood disorders. This study has provided the core information which is currently used to diagnose and predict clinical outcome of patients with major depression and bipolar mood disorders and has heavily influenced several DSM revisions, including DSM-5. Clinical Guide to Depression and Bipolar Disorder: Findings from the Collaborative Depression Study is a 'must-read' for clinicians who wish to explore the rationales for clinical diagnosis of mood disorders and the data used to support the current subtypes of depression. --David L. Dunner, M.D., FACPsych, Director, Center for Anxiety and Depression, Mercer Island, WA; Professor Emeritus, Department of Psychiatry and Behavioral Sciences, University of WashingtonMore than any other study, the Collaborative Depression Study has influenced our understanding of the clinical presentation and natural history of depression and mania, and shaped our view of mood disorders as chronic/recurrent conditions. This ground-breaking study, meticulously conducted over 30 years, has produced major insights into the importance of subclinical symptoms, switching from major depression to bipolar disorder, the impact of comorbid anxiety and substance misuse, the role of psychotic features, and the prediction of suicide, as well as providing influential advances in clinical assessment and statistical modeling. This volume summarizes many of the key findings that have emerged from the CDS, updates previously published results with final analyses based on 30 years of intensive follow-up, and traces the implications for the forthcoming fifth edition of the Diagnostic and Statistical Manual of Mental Disorders. It is a must-read for all mental health professionals concerned with understanding and treating mood disorders. --Daniel N. Klein, Ph.D., Professor and Chair, Department of Psychology, Stony Brook University, Stony Brook, NY From the Inside Flap Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study builds on research from the vastly influential NIMH Collaborative Depression Study (CDS) to provide clinicians with information they can use to assess, diagnose, treat, and understand how their patients will likely fare over the course of their illness. Prior to the CDS, there had been no longitudinal study of this scope and clinical focus, and the data has yielded knowledge that, enriched by ongoing research, provides essential guidance to mental health practitioners for effective treatment of their patients with mood disorders. The volume's editors and contributors are experts in mood disorder research, and they have created a work of uncommon value and utility. After a succinct but thorough summary of the history and methodology of the CDS, the book highlights the significance of CDS findings on mood disorders, including major depressive disorder and bipolar disorder, with emphasis on clinical course, interventions, and outcomes. Chapters on genetic factors and comorbidities provide critical context, and chapter-ending summaries of clinical implications help to highlight the importance of the CDS findings for clinical practice. Concise, authoritative, and evidence-based, Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study will be a welcome resource for mental health clinicians. About the Author Martin B. Keller, M.D., is Professor in the Department of Psychiatry and Human Behavior at Alpert Medical School, Brown University; and Chief Academic Strategic Planning and Director of the Mood and Anxiety Disorders Research Program at Butler Hospital in Providence, Rhode Island. William H. Coryell, M.D., is Professor in the Department of Psychiatry at the University of Iowa, Carver College of Medicine in Iowa City, Iowa. Jean Endicott, Ph.D., is Professor of Clinical Psychology in the Department of Psychiatry at College of Physicians and Surgeons, Columbia University; and Director of the Division of Clinical Phenomenology at the New York State Psychiatric Institute in New York, New York. Jack D. Maser, Ph.D., is Adjunct Professor in the Department of Psychiatry at the University of California, San Diego, in La Jolla, California. Pamela J. Schettler, Ph.D., is Principal Statistician in the Department of Psychiatry at the University of California, San Diego, in La Jolla, California; and Senior Research Associate in the Department of Psychiatry and Behavioral Sciences at the Emory University School of Medicine in Atlanta, Georgia.