PIMAFUCIN SUPPOSITORY

International Name (active ingredient): Natamycin Pharmacological action: antifungal drugs→ antifungal drugs for local use → antifungal antibiotics Manufacturer: Temmler Italia Srl Country of manufacture: Italy Release form: 100 mg vaginal suppository # 3 Issuing mode: Group III (without a prescription) Composition Vaginal suppositories: 1 suppository contains:  Active ingredient: Natamycin 100 mg. Excipients: cetyl alcohol 690 mg, solid fat 700 mg, sorbitol 460 mg, polysorbate 80-460 mg, sodium carbonate hydrate 69 mg, adipic acid 64 mg. PHARMACOLOGICAL PROPERTIES PHARMACODYNAMICS Polyol antibiotic of the macrolide group, characterized by a broad spectrum of action, exhibits fungicidal action. Natamycin binds sterols to cell membranes and causes the death of microorganisms by disrupting their integrity and function. Most pathogenic yeast fungi are susceptible to natamycin. Especially Candida albicans. Less sensitive to dermatophytes. Natamycin resistance is not found in clinic