LeuSynergy™ 120 capsules nuBioAge

An exercise and caloric restriction mimetic that improvesSirtuin and NAD+ functions. This low-dose leucinecompound is best known for its incredible enhancementof weight loss with GLP 1’s like semaglutide. LeuSynergy + GLP-1s has become afoundational protocol for weight lossand metabolism optimization. Cellular PathwaysDelivering the right dose of Leucine decreases the amountof NAD needed to activate SIRT-1. * Leucine at a concentration of 0.5mM was shown to decrease the kM of NAD by 50% With Leucine, LESS NAD+ is needed for SIRT-1 functions, improving NAD+ utilization in other cellular pathways. Why this matters: SIRT-1 Downstream EffectsStimulates caloric restriction and exercise pathways through these gene transcription factors::PGC-1a: The core regulator of mitochondrial biogenesis, PPAR: Regulate fat oxidation, AMPK: Master regulator of cell energy, NF-kB: Inhibition leads to decreased inflammation and oxidative stress  Clinical Studies Leucine-Resveratrol Synergy Human Pre-diabe