SAMe - 400mg Jarrow Formulas

Jarrow Formulas® SAMe 400 provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. With More of the Biologically Active S,S than R,S FormFound in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made naturally by microbiological fermentation and processed without chemical solvents to preserve 68-80% (S,S) SAMe. SAMe supports: Brain Metabolism and Mood*SAMe methylation reactions are involved in the synthesis ofphosphatidylcholine, a substantial constituent of grey matter within thebrain and cellular membranes.* It has also been proposed to be involvedin the formation or metabolism of neurotransmitters, which helps tosupport a balanced mood. Joint Health*SAMe supports the production of healthy connective tissue throughtranssulfuration.* In this transsulfuration process, critical componentsof connective tissue known as glycosaminoglycans (GAGs), includingglucosamine and chondroitin, are sulfated by SAMe metabolites toyield sulfated GAGs, such as glucosamine sulfate and chondroitinsulfate, the building blocks of cartilage. Liver Function*SAMe supports the synthesis of glutathione (GSH), which iscritical for antioxidant defenses and liver functions including phaseII detoxification. Supports: Joint Health*, Brain Metabolism and Mood*, Liver Function* Enteric-Coated 68-80% Active S,S Form Made Naturally By Fermentation Individually Blister-Packed Suggested use Adults take 1 tablet once a day on an empty stomach or as directed by your qualified healthcare professional.WARNING: Do not use if pregnant or nursing. Individuals with Parkinson’s disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinalupset in some persons. Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotoninre-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use.KEEP OUT OF THE REACH OF CHILDREN.STORE IN A COOL, DRY PLACE. Supplement facts Serving Size: 1 Tablet   Amount Per Serving %DV S-Adenosyl Methionine (from 800 mg of SAMe tosylate disulfate) 400 mg † †Daily Value (DV) not established. Other ingredients Microcrystalline cellulose, coating (hypromellose acetate succinate, stearic acid [vegetable source], triethyl citrate and riboflavin), glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol and sodium starch glycolate. No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.