Prunella Vulgaris (Self Heal, Xia Ku Cao) Spica Prunellae, Herpes, anti-estrogen, organic USA SELLER 2 oz

Prunella vulgaris is a flowering plant that is also known by the names Common Self-Heal, Xia Ku Cao, All Heal, Woundwort, Heart-of-the-Earth, Blue Curls, and Carpenter’s Herb. In a study Prunella vulgaris demonstrated that PVE30 is a potent antiviral agent against HSV infection. PVE30 inhibited the attachment of HSV by competing with HS and inactivated virions. In addition, PVE30 effectively restricted viral replication via the inhibition of NF-κB and TLR signalling and prevented HSV-1-induced necroptosis. The P. vulgaris polysaccharide PVE30 was shown to compete with heparan sulfate for interaction with HSV surface glycoprotein B and gC, thus strongly inhibiting HSV attachment to cells. In addition, PVE30 downregulated the expression of IE genes, which subsequently downregulated the expression of E and L viral gene products, and thus effectively restricted the yield of progeny virus. Further investigation confirmed that PVE30 inhibited TLR2 and TLR3 signalling, leading to the effecti