Fursultiamine (TTFD)

What is Fursultiamine (TTFD)? Fursultiamine is the common name for thiamine tetrahydrofurfuryl disulfide (TTFD). It is a synthetic derivative of thiamine (vitamin B1) designed for superior absorption and cellular uptake. Unlike water-soluble thiamine salts, fursultiamine is fat-soluble, allowing it to cross cell membranes and the blood-brain barrier more efficiently. It helps to restore thiamine-dependent enzymatic activity in the mitochondria, particularly in conditions that impair thiamine transport or metabolism. Fursultiamine bypasses normal intestinal transport mechanisms, making it more bioavailable than thiamine hydrochloride or thiamine mononitrate. It enters cells via passive diffusion and rapidly converts into active thiamine within the mitochondria, where it contributes to adenosine triphosphate (ATP) production for energy and nervous system function. Potential Fursulti