Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP

$390.00
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SOLU-KNEX® cleavable linker features a Val-Cit dipeptide. m-PEG8 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para-nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU-KNEX® ADC linkers integrate solubilizing moieties—such as PEG, amine-containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection and combination of these groups, making the linkers highly adaptable for diverse ADC and related applications. SOLU-KNEX® is a registered trademark of Tenova Pharmaceuticals, Inc. For research use only. Product Name Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C49H76N10O18 Molecular Weight 1093.199 Purity (HPLC) >= 95% S

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