BC-Cp
tenovapharma.com

BC-Cp

$390.00
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Tenova Pharma

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CLIP-tag is a modified version of the SNAP-tag. It is also a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. Unlike the SNAP-tag, which reacts with benzylguanine (BG)or chloropyrimidine (CP) derivatives, the CLIP-tag is engineered to specifically interact with benzylcytosine (BC)derivatives. This modification allows for distinct labeling applications, enabling researchers to use both SNAP-tag and CLIP-tag in the same experiment, providing flexibility in protein labeling and tracking. BC-Cp is a CLIP-tag substrate containg methylcyclopropene moiety for click chemistry applications. The methylcyclopropene moiety can act as a dienophile in inverse electron-demand Diels-Alder (iEDDA) reactions, where it reacts with 1,2,4,5-tetrazines (Tz) to form a stable bicyclic product. This reaction is useful in bioorthogonal chemistry for bioconjugation and molecular labeling without the need for catalysts, making it highly suitable for live-cell imaging and other bi

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