ACADM Polyclonal Antibody - E-AB-60486

ACADM Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-60486-60, E-AB-60486-120, E-AB-60486-200 Citations, Manuals and MSDS Available upon request. Abbreviation: ACADM Target Synonym: ACADM; ACAD1; MCAD; MCADH Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: IF Isotype: IgG Clonality: Polyclonal UNIProt ID: P11310 Background: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Concentr