ZicherRed Nucleic Acid Safe Gel Stain

ZicherRed is a highly sensitive and environmentally safe fluorescent nucleic acid dye for detection of DNA and RNA in agarose and polyacrylamide gels. ZicherRed Nucleic Acid Safe Gel Stain emits red fluorescence when bound to dsDNA, ssDNA, and RNA and replaces the need for the mutagenic ethidium bromide, commonly used in gels staining procedures for visualization of nucleic acids. ZicherRed is not cell-permeable and nonmutagenic in the Ames test. DNA visualization after staining with ZicherRed can be done using conventional gel imaging instruments (UV transilluminators). The blue LED illumination can be used too, however, ZicherRed stained nucleic acid bands will be less prominent. For blue LED transilluminators, we recommend our ZicherGreen Nucleic Acid Safe Gel Stain (catalog # ZGGS-701). The dye is efficiently removed from DNA by gel extraction or ethanol precipitation, and therefore does not interfere with downstream DNA manipulations such as restriction digestion, ligation, PCR, a