Muse^® Human B Cell Kit

The Muse® Human B Cell kit allows for determination of the B cell count, total lymphocyte count, and B cell percent of lymphocytes in human whole blood and peripheral blood mononuclear cell (PBMC) samples. Characterization of B cell counts and percentages enables a better understanding of the humoral immune response, insight into the mechanisms of autoimmune diseases, further research into factors that influence T cell responses, and improved vaccine development. The Muse Human B Cell kit detects and identifies lymphocytes and CD19+ B lymphocytes in both whole blood and PBMCs using a simplified, no-wash assay. Because CD19 is considered to be a characteristic B cell marker, it is commonly used in the routine immunophenotyping of B cells. Monoclonal antibodies cluster as CD19 detects all peripheral blood B cells.1 The simplified identification aids in understanding the role of B lymphocytes in development, response, and mechanism of disease. The Muse Human B Cell kit is optimized for