Artocarpus integrifolia Lectin (AIA) - Pure

Artocarpus integrifolia Lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The protein's structure explains its carbohydrate-binding specificity of T-antigen disaccharide Galß1,3GalNAc. Potent inhibitors of jacalin include D-galactose, ß-Met-Gal and 2-deoxy-α-D-galactose. This product comes in a stable lyophilized form. Specifications: Source: Artocarpus integrifolia (Jackfruit) Activity: Less than 0.5 ug /ml will agglutinate neuraminidase treated human erythrocytes. Carbohydrate Specificity: Galß1-3GalNAc Inhibitory Carbohydrate: Galactose or Melibiose Mito